Two games were contested on Tuesday as the knockout stage of the Copa Libertadores commenced with the Round of 16.
At Asuncion, Paraguay:
Igancio Scocco (36') and Marcelo Larrondo (87') each scored once as River Plate took the opening match of their two-game series with Club Guarani 2-0 on the road.
At Mendoza, Argentina:
Ramiro Benetti scored the only goal of the match in the opening minute as Gremio knocked off Godoy Cruz 1-0 on the road in their series opener.