The Round of 16 in the Copa Libertadores is set to continue on Wednesday with three games.
At Curitiba, Brazil:
Kayke Rodrigues scored twice (24', 67') as Santos took the opening match of their two-game series with Atletico Paranaense 2-1 on the road.
At Guayaquil, Ecuador:
Jonathan Alvez scored the lone goal of the contest in the second minute of second-half stoppage time as Barcelona SC defeated visiting Palmeiras 1-0 in their series opener.
At Cochabamba, Bolivia:
Gilbert Alvarez scored the only goal of Jorge Wilstermann's series-opening 1-0 victory over visiting Atletico Mineiro in the 41st minute.